Rabbit Anti-GABA , alpha3-Subunit Polyclonal antibody, Unconjugated

  • Rabbit Anti-GABA , alpha3-Subunit Polyclonal antibody, Unconjugated

    CatalogueID : 480016

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Target GABA alpha3-Subunit
Target Species Oryctolagus cuniculus
Unit 0.5 ml
Description GABA?, a3-Subunit, Rabbit Polyclonal Antibody (SKU 480016) specific to Rat and Mouse. This antibody is validated for use in WB. GABAA , a3-Subunit, Rabbit Polyclonal Antibody recognizes the expressed product of the Gabra3 gene, also known as gamma-aminobutyric acid (GABA) A receptor, alpha 3, MGC33793, GABRA3. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six as, four ßs and four ?s, plus alternative splicing variants of some of these subunits, have been identified.
Clonality Polyclonal