Doxorubicin. HCl

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Target/Molecule Synonym Topoisomerase II, DNA, Reverse transcriptase, RNA polymerase, Dnmt1, c-Myc, c-Jun
Specifications/Features

Mainfeature: Topoisomerase inhibitor

Brand/Trademark BIOMOL
Purity ≥95% (TLC)
Formula C27H29NO11. HCl
Molecular Weight 580.0
Keywords CAR/ATU| CAR/DTC/TOP| CDA/BCD| CEL/DNM| DNA/BGE| DNA/DNM| IMM/BIR| IMM/IND| NAT/AIA/ABA| NAT/CRR| NAT/CDR| NAT/DNR| NAT/IMO| NAT/TOX| DDI/SMM Inhibitor| Ligand| Inhibitor| Inhibitor| Inhibitor| Inhibitor Topoisomerase| DNA| Reverse transcriptase| Dnmt| c-Myc| c-Jun
Item Name Synonyms DXR . HCl| 14-Hydroxydaunomycin . HCl| Adriamycin . HCl| Doxorubicin . hydrochloride
Sample Type Red solid.
Original Item Name Doxorubicin . HCl
CAS Number 25316-40-9
Target Topoisomerase II, DNA, Reverse transcriptase, RNA polymerase, Dnmt1, c-Myc, c-Jun
Category Inhibitor: Ligand
Unit 25 mg
Description A broad spectrum antitumor agent. Induces DNA damage by intercalating into DNA and inhibiting topoisomerase II. Binds covalently to DNA. Inhbibits reverse transcriptase, RNA polymerase and the catalytic activity of Dnmt1. Immunosuppressive. Antineoplastic. Induces apoptosis. Down regulates c-myc and c-jun in doxorubicin-sensitive cells