Rat MCP-1

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Format Purity: >98% by SDS PAGE and HPLC analysis
Format: Purified recombinant protein expressed in E. coli - lyophilised
Target Tag/Conjugate Unconjugated
Species Rat
Target/Molecule Synonym Small inducible cytokine A2, CCL2
Applications Functional Studies
Accession Number Accession Number: NP_002973.1
Category Protein
Source/Expression System Recombinant
Original Item Name RECOMBINANT RAT MCP-1
References [1] Tse. K. P. Tsang. N. M. Chen. K. D. Li. H. P. Liang. Y. Hsueh. C. Chang. K. P. Yu. J. S. Hao. S. P. Hsieh. L. L. and Chang. Y. S.
MCP-1 Promoter Polymorphism at 2518 is associated with metastasis of nasopharyngeal carcinoma after treatment
[2] Xing. L. and Remick. D. G. et al.
Promoter elements responsible for antioxidant regulation of MCP-1 gene expression
[3] Roh. M. S. Lee. K. Y. Joo. E. J. Lee. N. and Kim. Y. S. et al.
No association of the MCP-1 promoter A-2518G polymorphism with bipolar disorder in the Korean population
[4] Moon. J. Y. Jeong. L. Lee. S. Jeong. K. Lee. T. Ihm. C. G. Suh. J. Kim. J. Jung. Y. Y. and Chung. J. H.
Association of polymorphisms in monocyte chemoattractant protein-1 promoter with diabetic kidney failure in Korean patients with type 2 diabetes mellitus
[5] Bartoli. F. Gesualdo. L. Niglio. F. Gentile. O. Penza. R. Leggio. S. Lasalandra. C. Campanella. V. and Magaldi. S.
Xanthogranulomatous pyelonephritis is associated with higher tissue expression of monocyte chemotactic protein-1
Molecule Name MCP-1
Unit 0.01 mg
Description Summary: This protein is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates. like psoriasis. rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Sequence Length (aa): 99 KEGG pathway: Cytokine-cytokine receptor interaction 04060 OMIM: NCBI [ 158105] Applications Tested: FN Cross-Reactivity: Rat Storage: Prior to reconstitution store at +4C. Following reconstitution store at -20C.This product should be stored undiluted.Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Stability: 3 months from date of reconstitution. Specificity: MCP-1 Specificity: MCP-1 Approx. Protein Conc: 0.1 mg/ml Endotoxin Level: