Bovine ANXA1

  • Contact Vendor

Format Purity: >95% pure (SDS PAGE). Sequential chromatography of EGTA eluted Ca2+ -dependent membrane binding proteins by DEAE Sepharose, Hydroxylapatite and Superose 12.
Format: Purified, Liquid
Target Tag/Conjugate Unconjugated
Target/Molecule Synonym Bovine Annexin I, Annexin-1, Annexin I, Lipocortin I, Calpactin II, Chromobindin-9, p35, Phospholipase A2 inhibitory protein, ANX1
Species Bovine
Original Item Name Bovine Annexin I
Molecule Name ANXA1
Category Native Protein
Source/Expression System Bovine Lung
Unit 0.1 mg
Description Background: Bovine Annexin IFunction: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. Binds muscle actin.Subcellular Location: Nucleus (By similarity). Cytoplasm (By similarity). Cell projection, cilium (By similarity). Basolateral cell membrane (By similarity). Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages (By similarity).Domain: A pair of annexin repeats may form one binding site for calcium and phospholipid.Ptm: Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity (By similarity).Similarity: Belongs to the annexin family.Similarity: Contains 4 annexin repeats.products ID: 248343Sp Accession Number: P46193Molecular Weight: 38952NCBI Name: Annexin A1Storage: Store at -70 C. Avoid multiple freeze/thaw cycles.Specificity: Annexin I, BovineType of Product: Purified Apoptosis and Signal Transduction ReagentsInactivation: Not applicableBuffer: 40 mM Tris, pH 7.5, 0.15 mM Sodium chloride, 0.1 mM DTTApplications Notes : Specific methodologies have not been tested using this product.Concentration: Concentration is lot specific