ABL1 Y253F

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Molecular Weight 125.4 kDa
Accession Number NP_005148.2, Y253F
Regulatory Status For Research Use Only. Not for any animal or human therapeutic or diagnostic use.
Target Tag/Conjugate His
Molecule Name c-abl oncogene 1, receptor tyrosine kinase
Gene Name c-abl oncogene 1, non-receptor tyrosine kinase, cAMP responsive element binding protein 5, c-abl oncogene 1, non-receptor tyrosine kinase, cAMP responsive element binding protein 5
Keywords human, mutant, Gleevec, resistant, proto-oncogene, nuclear, LanthaScreen, ABL, JTK7, bcr, c-ABL, p150, v-abl, _KWCPNT, N1417, R7444, KWCPNT_
Entrez GeneID 25, 25, 25, 9586, 9586, 9586
Gene Symbol CREB5, ABL1, ABL1, CREB5
NCBI Gene Aliases ABL,JTK7,bcr/abl,c-ABL,p150,v-ab, ABL,JTK7,bcr/abl,c-ABL,p150,v-ab, CRE-BP, CRE-BP
Applications Drug Discovery & Development:Enzyme & Protein Activity Assays:Kinase Activity:Kinase Biology:Kinase Proteins & Expression Reagents:Proteins, Expression, Isolation & Analysis:Target & Lead Identification & Validation
Unit 10 µg
Description The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The Y253F mutant is a Gleevec resistant form of ABL1.